ES-Cult™ M3120 is recommended as a base for the preparation of methylcellulose-based medium for the in vitro differentiation of mouse embryonic stem (ES) or induced pluripotent stem (iPS) cells into hematopoietic or endothelial progenitor cells. When supplemented with the appropriate additional components, ES-Cult™ M3120 can be used for the generation of embryoid bodies (EBs) from undifferentiated mouse ES or iPS cells.